WHAT NAD+ DOES
NAD+ helps your cells turn nutrients into fuel. Nearly every process in your body depends on that fuel.
Clinician-prescribed NAD+ to support your energy*
NAD+ for Energy is a compounded NAD+ injection you take at home, prescribed online by a licensed US clinician.
Starts at
$75
Coming soon - join the waitlist
Prescribed by a licensed clinician, Joyous NAD+ may help*:
Support your cells' energy production
Keep your focus clearer through the day
Support healthy aging
Compounded NAD+ for at-home injection, 1,000 mg vial.
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Third-party tested
Clinician-led
USP-compliant
US pharmacy
Where your energy comes from
NAD+ is a coenzyme that lives in each of your cells. It helps convert what you eat into energy your body can put to work.
ENERGY RUNS EVERYTHING
Focus at work, patience at home, a walk after dinner. All of it draws on the energy your cells make.
A SLOW DECLINE
Research shows NAD+ levels go down as we get older.¹ That can affect how well your cells produce energy.
SUPPORT YOUR CELLS
With a clinician's guidance, Joyous NAD+ may help support your cells so your energy feels steadier.*
What happens to NAD+ as you age
NAD+ occurs naturally in your body. But studies show that NAD+ levels tend to fall as we get older.¹
With less NAD+ available, your cells can have a harder time making energy. It's one part of the bigger picture of how energy changes with age.
What can change when NAD+ goes back up
Joyous NAD+ is prescribed by licensed clinicians to help replace some of the NAD+ your body loses with age.
Research on NAD+ boosters points to real, measurable changes. In a 60-day trial of 80 adults, people taking an NAD+ precursor had higher blood NAD levels, walked farther in a six-minute walk test, and rated their overall health better than people taking a placebo.²
59%
rise in NADH, an active form of NAD, in older men after one dose of an NAD+ precursor³
15%
less exercise fatigue for the same older men in that small study³
Steady support, not a quick buzz
NAD+ isn't caffeine. Instead of a short spike, it may help support the steady energy you rely on all day.*
That could mean getting through the mid-afternoon dip, staying engaged with the people around you, and holding your focus when the day gets busy.*
“When you're running on empty, even small healthy habits can feel like a lot. NAD+ is one of the building blocks your cells use to make energy. Supporting your NAD+ levels may help give you more to work with each day.*”
Dr. Bobbi Leben, Joyous Chief Medical Officer
Our quality standards
Joyous NAD+ is prepared by US-based pharmacy partners that follow USP compounding standards. Every batch is tested by an independent lab before it ships to you.
WHAT TO EXPECT
Made by US-based pharmacy partners
Compounded to USP standards
Third-party tested, batch by batch
Shipped to your door
From waitlist to your first dose
Step 1
Join the waitlist
Leave your email and we'll let you know as soon as Joyous NAD+ is available.
Step 2
Online clinician review
A licensed US clinician reviews your health history online and decides whether NAD+ is a good fit for you.
Step 3
Shipped to your door
If you're prescribed NAD+, it's shipped to your door with clear instructions for your at-home injections.
Step 4
Ongoing clinician support
Your care continues after the first prescription. Your clinician checks in on how you're doing and is there when you have questions.
FAQs
What is NAD+?+−
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NAD+ stands for nicotinamide adenine dinucleotide. It's a coenzyme that occurs naturally in every cell of your body. Your cells need it to turn nutrients into energy they can use.
NAD+ levels go down with age, which can affect how well your cells make energy. A Joyous clinician can prescribe compounded NAD+ injections to help support your levels, which may help you have more energy day to day.*
What will NAD+ feel like?+−
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NAD+ doesn't work like a stimulant. Don't expect a sudden burst of energy. Any effect tends to build gradually over time.
Some people notice small shifts, like clearer thinking, more even energy, or recovering better after activity.* Everyone responds differently, and some people may not notice a change.
How is NAD+ taken?+−
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Joyous NAD+ is a small injection you give yourself at home, just under the skin of your belly. It's similar to how many GLP-1 medications are taken. A typical schedule is one dose every 3 days.
You'll receive one 1,000 mg vial per month. Your clinician looks at your health history and builds a dosing plan for you.
How are NAD+ injections different from other forms of NAD+?+−
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Injections deliver NAD+ more directly.
A lot of oral supplements use precursors, such as NR (nicotinamide riboside) or NMN (nicotinamide mononucleotide). These are ingredients your body converts into NAD+. An injection gives you NAD+ itself and skips the digestive system.
Can I take NAD+ with a GLP-1 medication?+−
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Yes. NAD+ can be used alongside a GLP-1 medication.
The two act on separate pathways in the body and serve different goals. Tell your Joyous clinician about every medication you take, and they'll check that your full plan makes sense and is safe for you.
Are there any side effects?+−
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NAD+ is generally well tolerated, and many people have no side effects. Some people may have side effects like these, which are usually temporary:
- Flushing
- Nausea
- Headache
- Stomach cramping
- Dizziness
Your clinician will go over the possible risks with you and keep track of how you're doing, to make sure the treatment stays right for you.
Who should not take NAD+?+−
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NAD+ isn't safe or appropriate for everyone. You should not use NAD+ if you:
- Are pregnant or breastfeeding.
- Have a known moderate or severe allergy or hypersensitivity to NAD+, nicotinamide, or niacin.
- Have active cancer, are being treated for cancer, or have had cancer in the past 12 months.
- Have severe kidney disease: stage 4 chronic kidney disease or more advanced (eGFR under 30 mL/min/1.73m²).
- Have significant liver disease (Child-Pugh class B or C).
Unsure about any of these? Check with your healthcare provider before starting NAD+.
Be the first to hear when it's ready
Join the waitlist and we'll email you when Joyous NAD+ is available.
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We'll only email you about NAD+ availability. Unsubscribe anytime.
*Statements marked with an asterisk describe possible benefits, not promised results. Research on NAD+ is still developing, and some of the studies below looked at NAD+ precursors taken by mouth rather than NAD+ injections.
Prices shown are planned launch prices for Joyous NAD+ and may change before it becomes available.
¹The NAD+ chart is illustrative. It shows the general direction reported in a small cross-sectional study that measured NAD+ in the blood plasma of adults aged 20 to 87. It does not show actual or individual NAD+ levels.
Joyous NAD+ is available by prescription only, based on clinical need. A licensed clinician decides whether it's appropriate for you after reviewing your health history. Clinicians may use their professional judgment to prescribe NAD+ off-label.
Compounded medications are not FDA-approved, and the FDA does not review them for safety, effectiveness, or quality. The FDA has not evaluated or approved any product claims on this page.
Individual results vary. Joyous NAD+ is not available in all states. Joining the waitlist does not guarantee that you will be prescribed NAD+.
This page is for general information and is not a substitute for medical advice.
- The plasma NAD+ metabolome is dysregulated in "normal" aging. Rejuvenation Research, 2019.
- The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults. GeroScience, 2022.
- Acute nicotinamide riboside supplementation improves redox homeostasis and exercise performance in old individuals. European Journal of Nutrition, 2019.
- Therapeutic potential of NAD-boosting molecules: the in vivo evidence. Cell Metabolism, 2018.
- NAD+ in aging, metabolism, and neurodegeneration. Science, 2015.
- In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences. PNAS, 2015.
- The role of NAD+ metabolism and its modulation of mitochondria in aging and disease. npj Metabolic Health and Disease, 2025.