STRESS HITS
A demanding moment releases cortisol, often called the stress hormone. Your body gears up and stays tense.
Meet Oxytocin for Calm
A once-daily prescription tablet that may help you handle everyday stress, with a licensed clinician guiding your care.*
Starts at
$55
Coming soon - join the waitlist
It's designed to add to the oxytocin your body already makes, which may help*:
Lift your mood
Ease everyday stress
Support better sleep over time
Feel closer during intimacy
One small tablet a day, placed under your tongue to dissolve. No water needed.
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Third-party tested
Clinician-led
USP-compliant
US pharmacy
Everyday stress has a way of snowballing
A short fuse. Constant tension. Low energy. A mood that dips for no clear reason. Most people know these feelings. They're common signs of stress from your job, your family and everything else on your plate. With some extra support, they may become easier to manage.*
IT BUILDS UP
Stress that sticks around doesn't just fade. Over weeks and months, it can wear down your energy and how you feel day to day.
IT SPILLS OVER
It can seep into the rest of your life, from your mood to your workouts to the healthy habits you're trying to keep.
ROOM TO BREATHE
With less stress weighing on you, it's easier to put your energy where it counts.
Your body already makes it
Oxytocin is a small peptide made by your brain. It's released in moments of closeness, like a long hug, holding hands or being intimate with a partner.
It's one of the ways your brain signals that you're connected, present and safe, so your body can settle and you can open up.
In a study of 29 couples, women given oxytocin felt more relaxed during intimacy, and some found it easier to share their desires with their partner.⁴
CONNECTED
PRESENT
SAFE
Steadier on the days that ask a lot
When you feel calmer, it's easier to be present with the people and moments in front of you.
Oxytocin for Calm is meant to work alongside your body's own stress response. That may help hard days feel a little lighter.*
1x
dissolving tablet a day
Online
from clinician review to your door
“Oxytocin isn't new to your body. You already make it every day. Oxytocin for Calm adds to your own supply, which may help bring cortisol down, lift your mood and support better sleep over time.* It's not a sedative, so it won't knock you out.”
Dr. Bobbi Leben, Joyous Chief Medical Officer
Why get it through Joyous
Oxytocin for Calm will come with the same clinician-led care Joyous patients already get.
You answer health questions online. A licensed US clinician reviews them and decides whether oxytocin is right for you.
Your clinician is there after the first prescription, to answer questions and adjust your plan as needed.
Your clinician
Here to answer questions as you go
Online
Made with care, checked for quality
Your prescription is compounded by a licensed US pharmacy and shipped to your door.
OUR STANDARDS
Compounded by a licensed US pharmacy
Prepared to USP standards
Third-party tested
Dispensed only with a clinician's prescription
How it will work
Step 1
Join the waitlist
Leave your email. We'll let you know as soon as Oxytocin for Calm is available.
Step 2
Get reviewed online
Answer a few health questions. A licensed clinician reviews them and decides whether oxytocin is a good fit for you.
Step 3
Shipped to your door
If you're prescribed, your tablets are shipped straight to you. No pharmacy line, no extra trip.
Step 4
Ongoing clinician support
Your clinician stays available as you go, to answer questions and check how things are going.
FAQs
What is oxytocin?+−
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Oxytocin is a peptide that your body makes on its own. The hypothalamus, a small region deep in the brain, produces it. The pituitary gland then releases it, and it sends signals across your brain and body.
Levels rise when you feel close to others, such as when you hug someone or spend time with people you love. It's linked to feeling bonded, connected and positive.
It also has a role in stress. Oxytocin interacts with the system that governs your stress reaction, and it may help reduce how much cortisol your body releases.
Joyous Oxytocin is a compounded tablet you take once a day, prescribed by a licensed clinician. Alongside your other healthy habits, it may help support your mood, your sleep and the way you respond to stress.*
Why might I consider Joyous Oxytocin?+−
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Everyday pressure can wear you down during the day and keep you wound up at night. Joyous Oxytocin may help your body respond to that stress, support a better mood and help you sleep more soundly over time.*
How do I take Joyous Oxytocin?+−
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It's an orally disintegrating tablet, or ODT. Once a day, you place one small tablet under your tongue and let it dissolve. No water needed.
Pick a time of day that fits your routine. Sticking with the same time each day helps you stay on track.
Give the tablet time to dissolve completely. Chewing or swallowing it may mean your body absorbs less of it.
Are there any side effects?+−
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Most people tolerate oxytocin well, and side effects tend to be manageable. Ones to know about include:
- Headache
- Nausea
- Flushing
- Dizziness
- Drowsiness
- Irritability
- Increased thirst
Contact your clinician if a side effect is severe, gets worse or lasts longer than a few hours. Get emergency care right away if you have trouble breathing, significant swelling or any sign of an allergic reaction.
Will it make me drowsy?+−
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Oxytocin isn't a sedative, and it doesn't work like melatonin or other over-the-counter sleep aids. It isn't designed to put you to sleep shortly after you take it. Used daily, it may help improve how well you sleep over time.*
If it does make you drowsy, try moving your dose to the evening.
Can oxytocin help with libido?+−
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Oxytocin is closely tied to closeness and intimacy. Your body releases it during touch and sex. Research on oxytocin and desire is still early.
In a study of 29 couples, oxytocin didn't change sex drive itself, but women felt more relaxed and some found it easier to share their desires with their partner.⁴ In a 22-week trial of 30 women with sexual difficulties, sexual function improved with oxytocin, but it improved about as much with a placebo.⁵ Both studies used an oxytocin nasal spray, not a tablet.
Joyous Oxytocin is prescribed to help with everyday stress. If low desire is your main concern, tell your clinician. They can look at causes like stress, sleep, hormones and other medications.
How long would I take Joyous Oxytocin?+−
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There's no fixed timeline. Stress, mood and sleep rise and fall with what's happening around you, such as a busy stretch at work, changes at home or a few weeks of poor sleep.
You can keep taking it while it's helping, as long as your Joyous clinician agrees it's still a good fit for your goals.
Can I take Joyous Oxytocin with a GLP-1 medication?+−
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Yes. It can be prescribed alongside a GLP-1 medication.
Your clinician will review your full medication list, GLP-1 included, and confirm the combination is safe and suitable for you.
Can I take Joyous Oxytocin with my other medications?+−
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Before you start, share a full list of your medications and supplements with your clinician. This matters most for heart medications and any mental health medications.
Joyous Oxytocin is not a replacement for anything you're already prescribed, including SSRIs and other antidepressants. Keep taking your medications as directed, and talk with whoever prescribed them before you stop or change any of them.
Will Joyous Oxytocin help my anxiety or depression?+−
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No. Joyous Oxytocin is not a treatment for anxiety, depression or other diagnosed mental health conditions.
It doesn't replace therapy, and it doesn't replace medication you've been prescribed for these conditions.
Who should not take Joyous Oxytocin?+−
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Joyous Oxytocin isn't right for everyone. Don't use it if any of these describe you:
- You're pregnant, breastfeeding or trying to conceive
- You're allergic or sensitive to oxytocin or to any inactive ingredient in the tablet
- You have significant heart disease, such as high blood pressure that isn't controlled or an irregular heartbeat
- You have significant kidney or liver disease
Not sure if something on this list applies to you? Check with a healthcare provider before using Joyous Oxytocin.
Be the first to know
Oxytocin for Calm is coming to Joyous. Join the waitlist and we'll email you when it's available.
You're on the list. We'll email you when Joyous Oxytocin is available.
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We'll only email you about availability. Unsubscribe anytime.
*Possible benefits are not guaranteed. Individual results vary.
Prices shown are planned launch prices for Joyous Oxytocin and may change before it becomes available.
Oxytocin for Calm is available by prescription only. A licensed clinician decides whether it's right for you based on clinical need, and may use professional judgment to prescribe oxytocin off-label.
The FDA has not reviewed or approved any claims about this product. Compounded medications are not FDA-approved, which means the FDA does not review them for safety, effectiveness or quality before they reach patients.
Not available in all US states.
The studies below looked at oxytocin given as a nasal spray. They did not test the dissolving tablet.
- Goodin et al. Intranasal Oxytocin Administration is Associated With Enhanced Endogenous Pain Inhibition and Reduced Negative Mood States. The Clinical Journal of Pain. 2015.
- Cardoso et al. Intranasal oxytocin attenuates the cortisol response to physical stress: A dose–response study. Psychoneuroendocrinology. 2013.
- Doerr et al. The Effect of Intranasal Oxytocin on the Association Between Couple Interaction and Sleep: A Placebo-Controlled Study. Psychosomatic Medicine. 2022.
- Behnia et al. Differential effects of intranasal oxytocin on sexual experiences and partner interactions in couples. Hormones and Behavior. 2014.
- Muin et al. Effect of long-term intranasal oxytocin on sexual dysfunction in premenopausal and postmenopausal women: a randomized trial. Fertility and Sterility. 2015.