Joyous Sermorelin vial, Rx strength, 10 mg, on a sunlit stone ledge

Sermorelin for Muscle

A prescription peptide that helps your body produce more of its own growth hormone.

Starts at

$95

Coming soon - join the waitlist

With a clinician's guidance, Joyous Sermorelin may help*:

  • Hold on to lean muscle as you age

  • Improve your body composition

  • Keep you strong for daily life

A small under-the-skin shot you give yourself at home in the evening.

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  • Third-party tested

  • Clinician-led

  • USP-compliant

  • US pharmacy

Muscle shapes how you age

Muscle does more than move you. When it starts to slip, it can set off a chain of changes across your body.¹

Woman drinking water in a bright kitchen after a workout

METABOLISM SLOWS

With less muscle, your body burns less energy at rest. Weight gets easier to put on and harder to take off.

Man walking up outdoor stone steps in a park

DECLINE SPEEDS UP

Ongoing muscle loss is tied to greater health risks and a quicker decline as you age.

Woman resting on a yoga mat in her living room

ENERGY DIPS

Less muscle may bring more energy slumps and cravings that feel harder to manage.

Man lifting a dumbbell in a bright gym

STRENGTH HOLDS

Holding on to muscle is linked to living longer and staying healthier.

The changes you notice have a cause

As you get older, your body releases less growth hormone. After about age 30, the drop runs at roughly 15% per decade.²

Growth hormone helps your body keep muscle, recover after effort, and hold a healthy body composition. As levels fall, you may notice slower recovery, less strength, or a shift in your shape, even when your habits stay the same.

Woman carrying grocery bags up the steps of her homeGROWTH HORMONE RELEASE SLOWS WITH AGE20304050607080About 15% less each decade after age 30²

Supporting what your body already makes

Losing some muscle with age is common. It doesn't have to set the course for the years ahead.³

Joyous Sermorelin is a prescription peptide. It prompts the pituitary gland to send out more of your own growth hormone, mostly overnight while you sleep.

Paired with regular movement, it may help* you hold on to lean muscle as you age.

Couple hiking a forest trail together

Muscle supports more than strength

Muscle is active tissue that keeps working for you all day, even while you rest.

Keeping it as you age supports several parts of your health at once.

WHAT MUSCLE HELPS SUPPORT

  • Metabolism

  • Bone density

  • Blood sugar control

  • Hormone balance

  • Weight management

  • Steady energy

Man riding a road bike along a quiet country road

Muscle and a longer life

Muscle matters even more over the long run. In studies of older adults, more muscle mass has been linked with longer life.⁴

These figures describe muscle itself, not the effect of any medication.

Man carrying a crate of vegetables through a garden

20%

lower risk of death in older adults with the most muscle vs. the least⁴

3,659

older adults followed in a US national health survey⁴

“Muscle is closely tied to how long and how well people live. Keeping it takes more effort with each decade. Sermorelin doesn't give you growth hormone directly. It signals your body to make more of its own, which may help* you hold on to strength.”

Dr. Bobbi Leben, Joyous Chief Medical Officer

Checked for quality before it ships

Joyous works with a licensed US pharmacy to prepare Joyous Sermorelin. Every batch is tested by an independent lab before it's shipped to your door.

BEHIND EVERY VIAL

  • Prepared by a licensed US pharmacy

  • Every batch third-party tested

  • Compounded to USP standards

  • Shipped to your door

Close-up of a Joyous Sermorelin vial, Rx strength, 10 mg, on warm stone

How it will work

  1. Step 1

    Join the waitlist

    Leave your email. We'll let you know when Joyous Sermorelin is available.

  2. Step 2

    Online clinician review

    Answer questions about your health online. A licensed clinician reviews them and prescribes only if it's clinically appropriate.

  3. Step 3

    Shipped to your door

    If you're prescribed, your medication is shipped to your door. Your clinician walks you through the evening routine so you feel ready for your first dose.

  4. Step 4

    Ongoing clinician support

    Reach your clinician with questions along the way. They'll check in and adjust your plan as needed.

FAQs

What is sermorelin?
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Sermorelin is a peptide, a short chain of amino acids. Joyous Sermorelin is compounded by a pharmacy and prescribed by a licensed clinician. It's meant to support your body as some of its systems slow with age.

Over time, the processes that help you keep muscle, recover, and maintain a healthy body composition become less active.² This is expected as you get older. It can feel more obvious when your weight is changing.

Sermorelin acts on the pituitary gland, a small gland at the base of the brain, prompting it to put out more growth hormone. HGH therapy gives you growth hormone directly. Sermorelin instead helps your body make more of its own.

Since it works through your own hormone system, sermorelin may help* you keep lean muscle, bounce back after exercise, and age well.

How will sermorelin make me feel?
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Most people don't feel a distinct effect after each dose. Any changes tend to build slowly over time.

Some people say they recover better after exercise, keep muscle more easily, or have more energy overall. Others don't notice much from day to day but see their body composition change gradually.

Since sermorelin supports processes your body already runs, results are usually gradual and add up rather than arriving all at once.

Are there any side effects?
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Most people tolerate sermorelin well, and the risk of side effects is low. The ones people report most often are:

  • Mild irritation where you inject
  • Headache
  • Flushing

These are usually temporary. Your clinician will go over possible risks with you before you start and keep track of how you're doing, to make sure the treatment is still a good fit.

Can I take sermorelin with a GLP-1 medication?
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Yes. A clinician can prescribe sermorelin while you're on a GLP-1, and the two are often combined. Each has its own job. The GLP-1 is aimed at weight loss. Sermorelin may help* you keep muscle and recover well.

Tell your clinician about every medication you take. They'll review your whole plan to make sure it's safe and right for you.

How is sermorelin taken?
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Sermorelin is a small shot you give yourself at home, into the fatty layer under the skin. Many GLP-1 medications are given the same way.

You take it in the evening. Sermorelin prompts the pituitary gland to put out growth hormone, and your body does most of that while you sleep. An evening dose matches your body's own timing.

The usual schedule is five doses a week, as directed by your clinician. For most people, it's easy to build into the week.

On a weekly GLP-1 too? It's fine to take a sermorelin dose on the day of your GLP-1 shot.

Who should not take sermorelin?
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Sermorelin isn't a fit for everyone. Don't take it if:

  • You have cancer now or have had it before
  • You have or have had a pituitary tumor or pituitary disease. This includes pituitary adenomas, other tumors inside the skull, and conditions like acromegaly, where the body makes too much growth hormone
  • You're pregnant or breastfeeding
  • You're allergic or sensitive to sermorelin or to any ingredient in its formulation

Your clinician looks at your full health history before deciding if sermorelin is right for you.

Join the Joyous Sermorelin waitlist

Joyous Sermorelin isn't available yet. Leave your email and we'll tell you when it launches.

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*Statements marked with an asterisk describe possible benefits reported in published research. They are not a promise of any result. Numbered markers point to the sources listed below.

Prices shown are planned launch prices for Joyous Sermorelin and may change before it becomes available.

Joyous Sermorelin is available by prescription only. A licensed clinician decides whether to prescribe it based on your clinical need, after an online evaluation. Not everyone will qualify. Sermorelin may be prescribed off-label.

Joyous Sermorelin is a compounded medication. Compounded medications are not approved by the FDA, and the FDA does not review them for safety, effectiveness, or quality. Claims about this product have not been reviewed or approved by the FDA.

Individual results vary. Not available in all states. Images are for illustration only.

  1. * doi:10.1210/jcem.82.5.3943
  2. * doi:10.1016/j.beem.2013.05.003
  3. * doi:10.1155/2013/942030
  4. 1. doi:10.1093/ajcn/82.5.941
  5. 2. Fredrick JR, Blackman MR, Corpas E, et al. Growth Hormone and Aging. Endotext. MDText.com, Inc.; updated 2026 Mar 10.
  6. 3. doi:10.1002/rco2.9
  7. 4. doi:10.1016/j.amjmed.2014.02.007
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