120,000+ patients treated

Anxiety, treated at home

A low daily dose of a prescription medication, adjusted to you. Licensed clinicians, daily check-ins, and a troche that dissolves in your mouth at home.

See if I qualify
  • Free, no-commitment provider consultation
  • HSA/FSA accepted
“I have struggled with anxiety my whole life. Tried many unhealthy and prescribed remedies. None worked. Ketamine has been a game changer.”
W
WillJoyous patient, US
Friends laughing around a table outdoors

“It is so easy to let the little things go that I would normally obsess on.

Now my days are full of happiness and excitement.”

Monika, Joyous patient

Licensed clinicians + daily check-ins + 32 states

Low dose. Subtle by design.

Ketamine therapy at home: a low daily dose of a prescription medication, adjusted to you.

DoseSmall, daily, found with your clinician.
FeelingCoherent and aware. Not a trip.

Getting started takes minutes

  • Online assessmentAnswer a few questions, see if you qualify.
  • Meet your clinicianA licensed clinician assesses your symptoms and prescribes your protocol, by video.
  • Free shipmentMedication ships discreetly to your door.
Get started

Free, no-commitment provider consultation

Hands sliding the Joyous troche tray out of its purple sleeve
I embrace joy one moment at a time
“I have become a person I’ve never been able to be.”
J
Jade EchoJoyous patient, Trustpilot

Anxiety is a loop.
Ketamine works differently.

Glutamate, not serotonin. A different system than antidepressants.

87%cut their anxiety score in half or better (GAD-7, six weeks, n = 41,510)
59%reached the remission range for anxiety (GAD-7, six weeks)
16 daystypical time to cut a depression score in half (median)
78%felt relaxed in their body during treatment (n = 30,355)

From Joyous outcomes data on 66,727 patients. Patients who started with moderate-or-worse symptoms. Self-reported PHQ-9/GAD-7 scores. Individual results vary.

OutcomesDaily check-insThe science

A Joyous ketamine troche, scored into four
One small troche. Dissolves in your mouth.

Why people choose Joyous

Come for joy.

Most people don’t come to feel less bad. They come to feel good.

Feel good,
not just less bad

Two months in, many more patients report high positive emotion and high overall wellbeing.

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Free, no-commitment provider consultation

“Quite literally life saving. Having been living with depression for 22 years, I never knew life could be this … well, joyous!!”

Eva D

5.9%
27.3%
3.5%
20.7%
High positive emotion, at startHigh positive emotion, two months inHigh overall wellbeing, at startHigh overall wellbeing, two months in
Joyous outcomes data, n = 7,448. Positive emotion: 4 or 5 of 5. Wellbeing: average of 4+ of 5 across positive emotion, engagement, relationships, meaning, accomplishment.
How it works
Treatment starts low and rises in small steps only as tolerated, until your clinician finds your lowest effective dose. You check in daily, and the dose only moves when your clinician approves it.
Who it’s for
Most patients come for depression, anxiety and PTSD; many also with chronic stress and burnout, high-functioning anxiety or depression, grief and trauma, OCD, and chronic pain.
Who is screened out
Psychosis or bipolar I, active suicidal intent, uncontrolled high blood pressure, seizure history, a history of stroke or brain injury, pregnancy or breastfeeding, active or past substance use disorder. A licensed clinician screens out patients with any of these.

Join 120,000+ patients treating anxiety at home

Start with a
free consultation

Pick your plan

Best price

$129/mo with a 3-month commitment. Includes the medication.

Subscription includesHSA/FSA

$129/mo

  • ✓Medication & shippingIncluded
  • ✓Provider appointmentsIncluded
  • ✓Be Joyous™ patient platformIncluded
  • ✓Joyous Care supportIncluded
  • ✓Mental health resourcesIncluded
  • ✓Access to our patient communityIncluded
Get started

3-month commitment. HSA/FSA accepted. Not covered by insurance.

S

“Least expensive option for low dose oral ketamine. Everything is done online over zoom and its very easy.”

Stephen C., Trustpilot

Inside your subscription

Everything you need to get started, from your first visit to your daily check-ins.

Medication & shippingIncluded
Provider appointmentsIncluded
Be Joyous™ platformIncluded
Joyous Care supportIncluded

Your dose, found.

Start low. Check in daily. Your clinician adjusts until it’s right.

  1. Step 1Online assessment: see if you qualify.
  2. Step 2Meet your clinician by video.
  3. Step 3Medication ships discreetly to your door.
  4. Step 4Check in daily while your dose is adjusted.

Led by clinicians

Directed by licensed clinicians, the Joyous protocol is continuously adapted to each patient via a system of daily check-ins.

Medically reviewed by Bobbi Leben, MD.

Bobbi Leben, MD

Chief Medical Officer, Joyous. Double board certified.

Dr. Bobbi Leben

There is no health without mental health.

The Joyous team

A Public Benefit Corporation

The Joyous team

Most people don’t come to feel less bad. They come to feel good.

Come for joy.

65% of patients come for positivity and joy (n = 28,013)

Friends laughing at a table outdoors
Get started

Free, no-commitment provider consultation

66,727 patients in Joyous outcomes data

Come for joy

Friends laughing at a table outdoors
Come for joy.
Most people come to feel good.
The Joyous troche tray in hand
A small daily dose.
The Joyous team
Licensed clinicians and a care team.
Map of the states where Joyous is available
Available in 32 states.
→
120,000+ patients treatedLegitScript certifiedLegitScript certifiedPublic Benefit CorporationAvailable in 32 statesHSA/FSA accepted

Patient reviews on Trustpilot and Google

Real people, real words

Ketamine has been a game changer

I have struggled with anxiety my whole life. Tried many unhealthy and prescribed remedies. None worked. Ketamine has been a game changer. I would highly recommend this to anyone...

Will

The best treatment for depression and anxiety!

I started to feel major improvements in my depression within a couple of weeks. After about 2 months, I felt a tremendous relief in my anxiety symptoms!

Anjanette

My anxiety is almost completely gone

My journey was great. I took it for 5 months. Now my anxiety is almost completely gone. Also my depression went away. I feel a whole lot better than I have in ten years

Brandon G

Quite literally life saving

Having been living with depression for 22 years, I never knew life could be this … well, joyous!! I feel like I have superpowers.

Eva D

This treatment has saved my life

I don’t feel like a cloud is constantly over me, my ADHD has greatly improved, and my anxiety over small things is nearly nonexistent.

Jade Echo

Joyous Transformed my life

Amazing and life changing support. I have truly never felt better than the few months I was in treatment with Joyous. I recommend them to anyone who is struggling with mental health.

Heidi

It helped me grieve

It helped clear my mind from intrusive thoughts and feelings. It helped me sleep. It helped me grieve in an appropriate way.

Polly H.

Grateful for Joyous helped me through Depression and Anxiety

Ketamine has been a different experience no side effects, and a noticeable lift in my mood and clarity. It also helped me manage anxiety during some very challenging college courses.

Shelly V.

One of the best decisions I’ve ever made

I’m more active, I’m more patient with my family, I’m sleeping better & I’m getting back into my old hobbies. It’s been amazing.

Amber M.
Get started

Free, no-commitment provider consultation

Four kinds of ketamine therapy

Ketamine therapy comes in four main forms. Here is how they differ.

Joyous
IV infusion
Spravato
Higher-dose at home
Taken at home
You stay coherent and aware
No one needs to sit with you
Sitter often required
Dosing
Small daily dose
Series of sessions
With an oral antidepressant
Set weekly sessions
Adjusted from daily check-ins
FDA status for mental health
Off-label
Off-label
FDA-approved
Off-label

Source: joyous.team/ketamine-therapy, “What kinds of ketamine therapy are there?”

Get started

Free, no-commitment provider consultation

About Joyous

To enable individuals, families, communities, and humanity to live a Joyous life.

Joyous is a Public Benefit Corporation that puts patients’ well-being as our #1 priority, born out of a collaboration among medical experts, psychology specialists, and Silicon Valley technologists.

Meet the team

Questions people actually ask

Got a question we didn’t cover? Email [email protected] or text +1 (844) 774-0909.

Does ketamine therapy get you high?
No. The Joyous dose is designed not to: you stay coherent and aware throughout. Most people describe it as calming rather than intoxicating.
What does low-dose ketamine feel like?
Our low-dose protocol is designed to keep you fully present and coherent during treatment. After about 15 minutes you may notice a subtle calm and possibly some lightheadedness that quickly dissipates. Over the first weeks your dose is adjusted from your daily check-ins, so if the feeling isn’t right it will get adjusted.
How fast does ketamine therapy work?
Antidepressants are generally described as taking four to eight weeks to work. In the Joyous cohort the average depression score had dropped 38% by the end of week one, and the typical patient’s score was cut in half within about 16 days. That is a median; reaching the remission range took a median of 48 days.
Is at home ketamine safe?
At-home ketamine treatment rests on three things: a low daily dose designed not to produce a high, screening by a licensed clinician before you start, and daily check-ins so the dose only moves when your clinician approves it. You stay coherent and aware throughout; the most common side effect in Joyous outcomes data was drowsiness (about 1 in 4 patients in week one, fewer than 1 in 5 by week six). Do not drive for 1 to 2 hours after a dose.
Is ketamine legal?
Yes. Ketamine is a federally controlled prescription medication: legal when prescribed by a licensed clinician, and prescribed off-label for depression, anxiety and PTSD. Joyous clinicians prescribe it in 32 states.
Can I keep taking other medications?
Many patients continue their existing antidepressant during treatment. Your clinician reviews your current medications at your video assessment and decides what is compatible. Bring your medication list.
Do I need to be in therapy to do this?
No, but many people are. 38% of Joyous patients were in talk therapy at the same time, rising to 44% among those with moderate or worse symptoms. If therapy is out of reach, the Joyous patient app includes curated treatment courses and resources you can work through on your own.
How much does ketamine therapy cost?
Joyous costs $129 a month on the plan with a three-month commitment, or $159 a month with no commitment, which drops to $129 after three months. Both include the medication.
Does insurance cover ketamine therapy?
Insurance does not cover Joyous. HSA and FSA funds are accepted.

Conditions we treat

Joyous clinicians can prescribe ketamine for any psychiatric diagnosis where they judge it appropriate.

Most commonAnxietyLearn more
Most commonDepressionLearn more
Most commonPTSDLearn more
Chronic stressLearn more
Performance anxietyLearn more
Joyous

If you are in crisis, call or text 988, text HOME to 741741, or call the Suicide Prevention Lifeline at +1 (800) 273-8255.

Ketamine for mental health is prescribed off-label. The FDA has not approved ketamine for conditions such as depression or anxiety, where it is commonly used off-label. Medication is compounded specifically for you based on your clinician’s prescription. Outcomes are self-reported PHQ-9/GAD-7 scores from Joyous patients who started with moderate-or-worse symptoms; individual results vary. Not covered by insurance.

Joyous at-home ketamineFrom $129/mo · HSA/FSA accepted
See if I qualify