A low daily dose of a prescription medication, adjusted to you. Licensed clinicians, daily check-ins, and a troche that dissolves in your mouth at home.
“I have become a person I’ve never been able to be.”
J
Jade EchoJoyous patient, Trustpilot
Anxiety is a loop. Ketamine works differently.
Glutamate, not serotonin. A different system than antidepressants.
87%cut their anxiety score in half or better (GAD-7, six weeks, n = 41,510)
59%reached the remission range for anxiety (GAD-7, six weeks)
16 daystypical time to cut a depression score in half (median)
78%felt relaxed in their body during treatment (n = 30,355)
From Joyous outcomes data on 66,727 patients. Patients who started with moderate-or-worse symptoms. Self-reported PHQ-9/GAD-7 scores. Individual results vary.
“Quite literally life saving. Having been living with depression for 22 years, I never knew life could be this … well, joyous!!”
Eva D
5.9%
27.3%
3.5%
20.7%
High positive emotion, at startHigh positive emotion, two months inHigh overall wellbeing, at startHigh overall wellbeing, two months in
Joyous outcomes data, n = 7,448. Positive emotion: 4 or 5 of 5. Wellbeing: average of 4+ of 5 across positive emotion, engagement, relationships, meaning, accomplishment.
Treatment starts low and rises in small steps only as tolerated, until your clinician finds your lowest effective dose. You check in daily, and the dose only moves when your clinician approves it.
Who it’s for
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Most patients come for depression, anxiety and PTSD; many also with chronic stress and burnout, high-functioning anxiety or depression, grief and trauma, OCD, and chronic pain.
Who is screened out
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Psychosis or bipolar I, active suicidal intent, uncontrolled high blood pressure, seizure history, a history of stroke or brain injury, pregnancy or breastfeeding, active or past substance use disorder. A licensed clinician screens out patients with any of these.
I have struggled with anxiety my whole life. Tried many unhealthy and prescribed remedies. None worked. Ketamine has been a game changer. I would highly recommend this to anyone...
Will
The best treatment for depression and anxiety!
I started to feel major improvements in my depression within a couple of weeks. After about 2 months, I felt a tremendous relief in my anxiety symptoms!
Anjanette
My anxiety is almost completely gone
My journey was great. I took it for 5 months. Now my anxiety is almost completely gone. Also my depression went away. I feel a whole lot better than I have in ten years
Brandon G
Quite literally life saving
Having been living with depression for 22 years, I never knew life could be this … well, joyous!! I feel like I have superpowers.
Eva D
This treatment has saved my life
I don’t feel like a cloud is constantly over me, my ADHD has greatly improved, and my anxiety over small things is nearly nonexistent.
Jade Echo
Joyous Transformed my life
Amazing and life changing support. I have truly never felt better than the few months I was in treatment with Joyous. I recommend them to anyone who is struggling with mental health.
Heidi
It helped me grieve
It helped clear my mind from intrusive thoughts and feelings. It helped me sleep. It helped me grieve in an appropriate way.
Polly H.
Grateful for Joyous helped me through Depression and Anxiety
Ketamine has been a different experience no side effects, and a noticeable lift in my mood and clarity. It also helped me manage anxiety during some very challenging college courses.
Shelly V.
One of the best decisions I’ve ever made
I’m more active, I’m more patient with my family, I’m sleeping better & I’m getting back into my old hobbies. It’s been amazing.
Licensed clinicians✦Daily check-ins✦Available in 32 states✦HSA/FSA accepted✦Medically reviewed by Bobbi Leben, MD✦Licensed clinicians✦Daily check-ins✦Available in 32 states✦HSA/FSA accepted✦Medically reviewed by Bobbi Leben, MD✦Licensed clinicians✦Daily check-ins✦Available in 32 states✦HSA/FSA accepted✦Medically reviewed by Bobbi Leben, MD✦Licensed clinicians✦Daily check-ins✦Available in 32 states✦HSA/FSA accepted✦Medically reviewed by Bobbi Leben, MD✦
About Joyous
To enable individuals, families, communities, and humanity to live a Joyous life.
Joyous is a Public Benefit Corporation that puts patients’ well-being as our #1 priority, born out of a collaboration among medical experts, psychology specialists, and Silicon Valley technologists.
Got a question we didn’t cover? Email [email protected] or text +1 (844) 774-0909.
Does ketamine therapy get you high?
No. The Joyous dose is designed not to: you stay coherent and aware throughout. Most people describe it as calming rather than intoxicating.
What does low-dose ketamine feel like?
Our low-dose protocol is designed to keep you fully present and coherent during treatment. After about 15 minutes you may notice a subtle calm and possibly some lightheadedness that quickly dissipates. Over the first weeks your dose is adjusted from your daily check-ins, so if the feeling isn’t right it will get adjusted.
How fast does ketamine therapy work?
Antidepressants are generally described as taking four to eight weeks to work. In the Joyous cohort the average depression score had dropped 38% by the end of week one, and the typical patient’s score was cut in half within about 16 days. That is a median; reaching the remission range took a median of 48 days.
Is at home ketamine safe?
At-home ketamine treatment rests on three things: a low daily dose designed not to produce a high, screening by a licensed clinician before you start, and daily check-ins so the dose only moves when your clinician approves it. You stay coherent and aware throughout; the most common side effect in Joyous outcomes data was drowsiness (about 1 in 4 patients in week one, fewer than 1 in 5 by week six). Do not drive for 1 to 2 hours after a dose.
Is ketamine legal?
Yes. Ketamine is a federally controlled prescription medication: legal when prescribed by a licensed clinician, and prescribed off-label for depression, anxiety and PTSD. Joyous clinicians prescribe it in 32 states.
Can I keep taking other medications?
Many patients continue their existing antidepressant during treatment. Your clinician reviews your current medications at your video assessment and decides what is compatible. Bring your medication list.
Do I need to be in therapy to do this?
No, but many people are. 38% of Joyous patients were in talk therapy at the same time, rising to 44% among those with moderate or worse symptoms. If therapy is out of reach, the Joyous patient app includes curated treatment courses and resources you can work through on your own.
How much does ketamine therapy cost?
Joyous costs $129 a month on the plan with a three-month commitment, or $159 a month with no commitment, which drops to $129 after three months. Both include the medication.
Does insurance cover ketamine therapy?
Insurance does not cover Joyous. HSA and FSA funds are accepted.
Conditions we treat
Joyous clinicians can prescribe ketamine for any psychiatric diagnosis where they judge it appropriate.