Not yourself lately?

At-home ketamine treatment for depression and anxiety.

A low daily dose, prescribed by a licensed clinician after a video appointment and delivered to your door. From $129/month.Prescribed online by a licensed clinician, delivered to your door. From $129/month.

Step 1 of 3 · Tap one to start

Pick what's been weighing on you mostPick what's weighing on you most

1Pick one below
2Short assessment, about 5 minutes
3Free video appointment with a licensed clinician

1Pick one
25-min assessment
3Free video visit

Free appointment · no credit card · HSA/FSA
★4.7 Trustpilot · 120,000+ patients

Licensed clinicians✦Daily check-ins✦Available in 32 states✦HSA/FSA accepted✦Medically reviewed by Bobbi Leben, MD✦From $129/mo✦Licensed clinicians✦Daily check-ins✦Available in 32 states✦HSA/FSA accepted✦Medically reviewed by Bobbi Leben, MD✦From $129/mo✦Licensed clinicians✦Daily check-ins✦Available in 32 states✦HSA/FSA accepted✦Medically reviewed by Bobbi Leben, MD✦From $129/mo✦Licensed clinicians✦Daily check-ins✦Available in 32 states✦HSA/FSA accepted✦Medically reviewed by Bobbi Leben, MD✦From $129/mo✦

“I feel calm and collected and not so reactive.

Even my children notice that in me.”

The neuroscience

Not another serotonin treatment.
A different system.

Tap to compare ↑

Ketamine modulates glutamate, which can help the brain form new connections and loosen old thought loops. That's called neuroplasticity.

Stuck
Signal
Rebuild

Sources

Moda-Sava et al., Science 2019 · Li et al., Science 2010 · Wang, Kavalali & Monteggia, Cell 2022

Illustration

Not a quick fix.
Most cut their symptoms in half by week six.

Joyous patients who started with moderate or worse symptoms.

“My anxiety over small things is nearly nonexistent.” Jade Echo, Joyous patient

87%

with anxiety cut their score in half or better (GAD-7, six weeks)

86%

with depression cut their score in half or better (PHQ-9, six weeks)

Not easy cases. Most Joyous patients had lived with their symptoms for over two years, and about 29% had tried three or more antidepressants.

* Patients who started with moderate-or-worse symptoms · six weeks · self-reported PHQ-9/GAD-7 scores · individual results vary.

Sources

Outcomes · Ketamine for anxiety · The science

A Joyous ketamine troche, scored into four — One small troche. Dissolves in your mouth.

Licensed clinicians + daily check-ins + 32 states

Low dose. Not a trip.

One small troche a day that dissolves in your mouth. You stay coherent and aware, and get on with your day.

Dose

5-20×lower than standard clinical doses

Feeling

78%

felt relaxed in their body during treatment

Daily check-ins · 30,355 patients

You stay coherent and aware. Not a trip.

Hands sliding the lilac Joyous troche tray out of its purple pack — Your troches arrive in this pack. Slide the tray out, take one a day.

Dr. Bobbi Leben, Joyous Chief Medical Officer — Who’s behind your care
Led by *clinicians.*
“Anxiety isn’t a character flaw. It’s a pattern your brain learned, and patterns can change. My job is to find the right dose and keep adjusting it with you.”

**Bobbi Leben, MD**Co-founder and Chief Medical Officer, Joyous · Double board certified

See if treatment is right for me

Free appointment · no credit card needed

★ 4.7 on Trustpilot · 2,000+ reviews

Real people, real words

Ketamine has been a game changer

I have struggled with anxiety my whole life. Tried many unhealthy and prescribed remedies. None worked. Ketamine has been a game changer. I would highly recommend this to anyone...

Will

My anxiety is almost completely gone

My journey was great. I took it for 5 months. Now my anxiety is almost completely gone. Also my depression went away. I feel a whole lot better than I have in ten years

Brandon G

The best treatment for depression and anxiety!

I started to feel major improvements in my depression within a couple of weeks. After about 2 months, I felt a tremendous relief in my anxiety symptoms!

Anjanette

See if treatment is right for me

Free appointment · no credit card needed

Questions people actually ask

Does ketamine work for anxiety and depression?

In Joyous patient data, among patients who started with moderate or worse anxiety, 87% cut their GAD-7 score in half or better within six weeks and 59% reached the remission range. For moderate or worse depression, 86% cut their PHQ-9 score in half or better and 54% reached the remission range. Self-reported scores; individual results vary.

Does ketamine therapy get you high?

No. The Joyous dose is designed not to: you stay coherent and aware throughout. Most people describe it as calming rather than intoxicating.

Is at home ketamine safe?

At-home ketamine treatment rests on three things: a low daily dose designed not to produce a high, screening by a licensed clinician before you start, and daily check-ins so the dose only moves when your clinician approves it. You stay coherent and aware throughout; the most common side effect in Joyous outcomes data was drowsiness (about 1 in 4 patients in week one, fewer than 1 in 5 by week six). Do not drive for 1 to 2 hours after a dose.

Who is ketamine therapy not right for?

Psychosis or bipolar I, active suicidal intent, uncontrolled high blood pressure, seizure history, a history of stroke or brain injury, pregnancy or breastfeeding, active or past substance use disorder. A licensed clinician screens out patients with any of these.

Can I keep taking other medications?

Many patients continue their existing medication during treatment. Your clinician reviews your current medications at your video assessment and decides what is compatible. Bring your medication list.

How much does ketamine therapy cost?

Joyous costs $129 a month on the plan with a three-month commitment, or $159 a month with no commitment, which drops to $129 after three months. Both include the medication.

Got a question we didn’t cover? Email [email protected] or text +1 (844) 774-0909.

Start with a free appointment.

A licensed clinician will tell you if low-dose ketamine is right for you. No credit card needed.

Today

Free video appointment. No credit card.

If you’re approved

$129/mo

3-month plan, or $159/mo month to month.

Medication, appointments and daily check-ins included · HSA/FSA accepted · not covered by insurance

See if treatment is right for me

Free appointment · no credit card needed

Public Benefit Corporation
Available in 32 states
120,000+ patients

At-home ketamine treatment for depression and anxiety.

Pick what's been weighing on you mostPick what's weighing on you most

Not another serotonin treatment.A different system.

Not a quick fix.Most cut their symptoms in half by week six.

Low dose. Not a trip.

Real people, real words

Ketamine has been a game changer

My anxiety is almost completely gone

The best treatment for depression and anxiety!

Questions people actually ask

Start with a free appointment.

Not another serotonin treatment.
A different system.

Not a quick fix.
Most cut their symptoms in half by week six.