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At-home ketamine therapy for anxiety & depression. Clinician-directed.
See if I qualifyFrom $129/month — medication and care included.
Real patients, real numbers
100,000 patients treated, the numbers below are theirs.
A different mechanism — and a faster answer.
Low libido, weight gain, feeling not much at all — the side effects many of our patients come to escape. Ketamine works through a different mechanism than SSRIs, with none of these side effects, and typically much faster. Your clinician will talk through whether it fits alongside what you're taking now.
16 days
is how long it took the typical patient's depression score to fall by half.
Days 1–12
13–24
25–36
37–49
PHQ-9 · 43,563 patients
Calm and clarity
The spinning thoughts, the short fuse, the work of holding it together. The Joyous ketamine protocol helps reduce anxiety and shift your perspective. No sedation, no being taken out of your life — old thought loops quieting while life keeps going.
87%
of patients with moderate or worse anxiety cut their score in half — or better — within six weeks.
0–4
Minimal
5–9
Mild
10–14
Moderate
15–21
Severe
GAD-7 · 41,510 patients
You didn't come here just to be less depressed.
More than half describe an openness that helped them explore their feelings — a sentence nobody has ever said about an SSRI. Most improve on measured wellbeing: positive emotion, engagement, meaning, relationships. Less like being treated. More like coming back to life. More Joy.
78%
of patients have reported feeling relaxed in their body — nearly 8 in 10.
A few
Some
Most
Nearly all
Patient check-ins · PERMA wellbeing
For most people here, this isn't the first attempt.
Most Joyous patients had carried their symptoms for more than two years before they arrived. Our treatment has shown high efficacy across depression conditions — working faster than SSRIs typically do, and without the weight gain or low libido that bring so many patients here.
86%
cut their depression score in half or better within six weeks — and 54% reached the remission range.
0–4
Minimal
5–9
Mild
10–14
Moderate
15–20
Severe
PHQ-9 · 43,563 patients
In their own words
The words our patients use the most on Trustpilot.
The 12 words patients use most across 305 four- and five-star Trustpilot and Google reviews (11 Jun–9 Sep 2026), each counted once per review. Share of language, not a measure of treatment outcomes. Individual results vary.
Why Joyous
Licensed medical providers evaluate every patient. Your dedicated care team monitors your progress daily — not just a prescription and a "good luck."
Other at-home ketamine providers charge $300–$900/month. Joyous starts at just $129/month with daily monitoring included. HSA and FSA accepted.
Treat at home, on your schedule. No clinic visits, no waiting rooms, no commute. Your medication is shipped discreetly to your door every month.
86% cut their depression score in half or better within six weeks — and 87% did the same for anxiety. Microdose ketamine treats root causes through neuroplasticity — not just masking symptoms.
The Science
Unlike traditional antidepressants that target serotonin, ketamine works through a different pathway — boosting glutamate signaling to trigger neuroplasticity, your brain's natural ability to form new neural connections and repair pathways damaged by chronic stress.
Joyous uses psycholytic (low) doses — 5 to 20 times lower than clinical settings. No hallucinations, no downtime. Over 89% of patients report symptom improvement within the first month.
Explore the research →
Explore the research →
patients have chosen Joyous to take back their mental health
What happens next
Book a free consultation with a licensed Joyous provider. No credit card needed. Just the first step toward the life you deserve.
See if I qualify