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Joyous for Clinics
Joyous partners with clinics to offer at-home, low-dose ketamine care for depression and anxiety. You stay the prescriber and keep the relationship. Joyous supplies the medication, checks in with your patients every day, and sends you their progress before each visit.
Free for clinics to join. No platform fees.
Who does what
Your clinic
Prescribes, sets the plan, sees the patient monthly, makes every clinical decision.
Joyous
Onboards the patient, ships medication, runs daily check-ins and validated scales, flags risk, reports back to you.
Your patient
Doses at home, answers a one-minute daily check-in, attends follow-ups.
22M+doses delivered
100,000+patients treated
32states across the U.S.
At-home care since2022
The gap
Between visits, most clinics have almost no signal. A relapse, a side effect or a missed-dose spiral can be weeks old by the next appointment. Measurement-based care improves outcomes, but it is hard to run by hand.
Mood, sleep, adherence and side effects captured each day the patient checks in.
PHQ-9 and GAD-7 on schedule, weekly C-SSRS suicidality screening with RN follow-up.
A progress summary (dose, PHQ-9, GAD-7, check-ins) arrives before each follow-up.
How it works
You share your clinic's Joyous sign-up link. The patient verifies identity, signs consents and sets up their monthly plan in a few minutes.
Send the buccal troche Rx electronically from your EMR to the Joyous Partner Pharmacy, SmartScript (Oshkosh, WI), a specialist compounding pharmacy. Controlled substance: e-Rx only, no fax or paper.
The pharmacy fills and ships to the patient's door, signature required. Medication is included in the patient's plan.
The patient scans the QR code in the box, picks a start date and begins a one-minute daily check-in. Scales and C-SSRS run on schedule.
Progress reports and risk flags come to you, routed per the escalation protocol you set at onboarding.
You see the patient at about 3 weeks, then monthly, adjust the plan and write the next script. No automatic refills.
Outcomes
From 66,727 Joyous patients who started with moderate-or-worse symptoms.
86%
Response: score cut in half or better
54%
Reached the remission range (score under 5)
16days
Median time to response. 48 days to the remission range.
87%
Response: score cut in half or better
59%
Reached the remission range (score under 5)
15days
Median time to response. 45 days to the remission range.
Real-world outcomes data from 66,727 Joyous patients. Patients who started with moderate-or-worse symptoms · six weeks · self-reported PHQ-9/GAD-7 scores · individual results vary.
Clinical approach
Compounded racemic ketamine troches, alcohol-free and absorbed buccally (behind one's cheek), with an estimated 25–30% bioavailability. Daily dosing starts at 15 mg and rises in 15 mg steps as tolerated, titrated to response, up to a maximum of 120 mg. Sub-anesthetic and psycholytic: patients stay present, coherent, and aware.
Medical eligibility screening, PDMP checks, weekly C-SSRS with RN follow-up, blood-pressure monitoring at dose increases for patients with controlled hypertension or on stimulants, and a slow-absorbing troche that limits misuse.
Ketamine is a Schedule III controlled substance. Racemic ketamine for depression and anxiety is prescribed off-label, at the prescriber's clinical judgment. Esketamine (Spravato®) is the FDA-approved form for treatment-resistant depression.
Summary only. Full eligibility criteria and the clinical primer are shared during onboarding.
For your practice
There is no cost for clinics to join. Your patient pays Joyous one monthly subscription that includes medication, monitoring and support: $99/month.
Joyous surfaces information and escalates. It never changes your plan.
A BAA with your practice before any data is shared; patients sign a release so their progress comes back to you.
Scored measures and monitoring records for your chart, to support the services your clinic provides and bills.
Risk flags route to you on your terms; imminent-risk pathways are agreed up front.
Billing
Your clinic bills for the services you and your staff provide, through your own payers, as you do today. The codes below are ones practices commonly use for medication management and behavioral health care management. Whether any of them apply to a given patient is a decision for your clinic and your billing team.
| Service your clinic provides | Codes commonly used | Typical requirements |
|---|---|---|
| Medication-management visit | CPT 99213 · 99214 · 99215 | Established-patient E/M visit, leveled by medical decision-making or total time. In person or telehealth per payer rules. |
| Psychiatric Collaborative Care (CoCM) | CPT 99492 · 99493 · 99494 | A treating practitioner, a behavioral health care manager and a psychiatric consultant; a registry with validated measures; monthly time thresholds; patient consent. |
| General Behavioral Health Integration (BHI) | CPT 99484 | At least 20 minutes per month of care-management services by the practitioner or clinical staff, with ongoing measurement and patient consent. |
Scored PHQ-9 / GAD-7 results, check-in history and monitoring records your clinic can use in its own documentation.
Joyous's own monitoring, data collection or medication. The patient pays Joyous directly for those.
Informational only, not billing, coding or legal advice. Joyous does not guarantee coverage or reimbursement. Codes, requirements and payment vary by payer, state, setting and year; confirm with your payers and your billing or compliance team before submitting any claim.
Getting started
01
15 minutes on your patient population and workflow.
02
License check, partner agreement and HIPAA BAA.
03
Pharmacy favorite in your EMR, summary cadence, escalation routing.
04
Share your sign-up link; monitoring starts on day one.
Thanks. We'll reply within one business day.
Book a 15-minute callSomething went wrong. Email [email protected].
Pick a time that works for you. A 15-minute call with our partnerships team, booked straight onto our calendar.
Book a 15-minute callOr email us
[email protected]You are. Your clinic prescribes, manages the medication and makes all clinical decisions. Joyous provides monitoring, support and fulfillment.
Joyous currently serves patients in 32 states. We confirm coverage for your patients on the intro call.
Yes. Joyous troches are compounded to a specific formulation, so the program's medication is dispensed only by the Joyous Partner Pharmacy, a specialist compounding pharmacy (SmartScript, Oshkosh, WI). Its cost is included in the patient's $99 monthly plan. Patients who prefer a different pharmacy can be treated by your clinic outside the Joyous program.
$99 a month, medication included. Your own visits are billed by your clinic as usual.
Your clinic bills for the services it provides, such as follow-up visits and, where your practice meets the requirements, care management. See the codes clinics commonly use above, and confirm with your billing team.
Weekly C-SSRS screening and daily check-ins are reviewed by Joyous RNs. Flags route to you per the escalation protocol agreed at onboarding, with imminent-risk pathways defined in advance.
Educational information for licensed clinicians. Not a substitute for full prescribing information or clinical judgment. Ketamine is a Schedule III controlled substance; racemic ketamine for mood disorders is prescribed off-label. Individual results vary and no outcome is guaranteed.
If someone is in crisis, call or text 988, or text HOME to 741741.
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